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Onyx Axiom

A next‑generation topical antifungal for onychomycosis — combining the safety of topical therapy with efficacy approaching oral drugs, via a novel lyotropic liquid crystal drug‑delivery system.

Therapeutics Topical antifungal · Lyotropic liquid crystal drug delivery
Onyx Axiom founders.
The science · The story

How the company was formed, and what it is building.

Onyx Axiom is developing a next‑generation topical treatment for onychomycosis (toenail fungus) using a novel lyotropic liquid crystal drug‑delivery system to enhance the efficacy of terbinafine while avoiding the systemic side effects of oral antifungals.

Proto Axiom formed Onyx Axiom in 2025, licensing the underlying IP into Australia under an exclusive global licence.

A Phase IIb clinical trial is currently under way.

Founded
2025
Origin
Melbourne
Sector
Therapeutics
Modality
Topical antifungal · Lyotropic liquid crystal drug delivery
Leadership

Founders and key team.

Dr. Paul Gavin
Dr. Paul Gavin
Chief Executive Officer · Commercial Founder
Melbourne
Lawrence Gozlan
Lawrence Gozlan
Director · Commercial Founder
Proto Axiom Strategic Advisor
Anthony Liveris
Anthony Liveris
Director
Proto Axiom (founding investor)
Programme status

Where the programme is now, and what comes next.

Now
Phase IIb clinical trial of topical terbinafine for onychomycosis.
In the press

Recent news.

[ Press mentions to be added as they publish. ]